extrinsic apoptotic signaling pathway

The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.

• Code: GO:0097191
• Source: Gene Ontology
• Alternative labels: extrinsic apoptosis extrinsic apoptotic signalling pathway extrinsic apoptotic signaling pathway in presence of ligand death receptor-mediated apoptosis extrinsic apoptotic pathway