tumor necrosis factor production

The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.

• Code: GO:0032640
• Source: Gene Ontology
• Alternative labels: TNF alpha biosynthesis tumor necrosis factor secretion TNF-alpha biosynthesis TNF-alpha production TNF biosynthetic process tumor necrosis factor-alpha production tumor necrosis factor biosynthesis tumor necrosis factor anabolism cachectin production tumor necrosis factor biosynthetic process tumor necrosis factor synthesis Tnfa production TNF biosynthesis TNF production TNF-alpha biosynthetic process tumor necrosis factor formation