nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.

• Code: GO:0000184
• Source: Gene Ontology
• Alternative labels: mRNA degradation, nonsense-mediated decay nonsense-mediated mRNA decay nuclear mRNA catabolic process, nonsense-mediated decay mRNA catabolic process, nonsense-mediated mRNA breakdown, nonsense-mediated decay mRNA catabolism, nonsense-mediated