MAPK cascade

An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.

• Code: GO:0000165
• Source: Gene Ontology
• Alternative labels: MAPKKK cascade ERK/MAPK cascade MAPKKK cascade during sporulation MAPK signaling MAP kinase cascade MAPK signalling MAP kinase kinase kinase cascade MAPK signal transduction mitogen-activated protein kinase cascade