SU4312

A member of the class of oxindoles that is 3-methyleneoxindole in which one of the hydrogens of the methylene group has been replaced by a p-(dimethylamino)phenyl group. SU 4312 is a vascular endothelial growth factor (VEGF) receptor protein tyrosine kinase 1/2 and platelet derived growth factor (PDGF) receptor inhibitor. It also inhibits the neuronal nitric oxide synthase (NOS) and exhibits neuroprotection against NO-mediated neurotoxicity.

• Code: CHEBI:92369
• Source: CHEBI
• Alternative labels: 3-(4-dimethylamino-benzylidenyl)-2-indolinone 3-[4-(dimethylamino)benzylidene]-1,3-dihydro-2H-indol-2-one 3-[[4-(dimethylamino)phenyl]methylidene]-1H-indol-2-one DMBI SU-4312 SU 4312