acadesine

A 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects.

• Code: CHEBI:28498
• Source: CHEBI
• Alternative labels: 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide GP-1-110 5-amino-1-beta-D-ribofuranosyl-4-imidazolecarboxamide 5-amino-1-beta-ribofuranosyl-imidazole-4-carboxamide 5-amino-4-imidazolecarboxamide ribofuranoside acadesinum 5-amino-1beta-D-ribofuranosylimidazole-4-carboxyamide 5-aminoimidazole-4-carboxamide ribonucleoside AICAr acadesine EC Number 220-097-5 AIC-Riboside 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide N(1)-(beta-D-ribofuranosyl)-5-aminoimidazole-4-carboxamide AICA-riboside acadesina 5-amino-1-ribofuranosylimidazole-4-carboxamide GP 1-110