tacedinaline

A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.

• Code: CHEBI:90195
• Source: CHEBI
• Alternative labels: Acetyldinaline CI-994 4-(Acetylamino)-N-(2-aminophenyl)benzamide CI 994 C.I. 994 tacedinaline tacedinalina 4-acetamido-N-(2-aminophenyl)benzamide N-acetyldinaline